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前列腺切除术后尿失禁:关于诊断与管理的一切

Postprostatectomy incontinence: all about diagnosis and management.

作者信息

Bauer Ricarda M, Bastian Patrick J, Gozzi Christian, Stief Christian G

机构信息

Urologische Klinik und Poliklinik, Ludwig-Maximilians-Universität München, Klinikum Grosshadern, Munich, Germany.

出版信息

Eur Urol. 2009 Feb;55(2):322-33. doi: 10.1016/j.eururo.2008.10.029. Epub 2008 Oct 23.

Abstract

CONTEXT

The ever-increasing number of radical prostatectomies entails an increasing number of patients suffering from postprostatectomy stress incontinence despite improved surgical techniques. We provide an overview of the current diagnosis and treatment of postprostatectomy stress incontinence.

OBJECTIVE

To review previous and recent literature on this subject and to assess the current standards of diagnosis and management of postprostatectomy incontinence.

EVIDENCE ACQUISITION

The PubMed database was searched, and all articles published since 2000 were evaluated.

EVIDENCE SYNTHESIS

This review presents the current recommended diagnostic tools and available noninvasive and invasive treatment options.

CONCLUSIONS

The European Association of Urology (EAU) recommends a two-stage assessment for diagnosis of postprostatectomy incontinence. Noninvasive therapy, pelvic floor-muscle training and biofeedback, is recommended in early postoperative and mild incontinence. Pharmacological treatment with duloxetine is especially effective in combination with physiotherapy, where it synergistically improves the continence rate. For surgical treatment, the insertion of an artificial urinary sphincter, AS-800, is still the gold standard. In recent years, several minimal invasive treatment options have been introduced with different rates of success, but they have not yet surpassed the results of the artificial sphincter.

摘要

背景

尽管手术技术有所改进,但根治性前列腺切除术的数量不断增加,导致前列腺切除术后压力性尿失禁的患者数量也在增加。我们概述了目前前列腺切除术后压力性尿失禁的诊断和治疗方法。

目的

回顾关于该主题的既往和近期文献,并评估前列腺切除术后尿失禁的当前诊断和管理标准。

证据获取

检索了PubMed数据库,并对2000年以来发表的所有文章进行了评估。

证据综合

本综述介绍了当前推荐的诊断工具以及可用的非侵入性和侵入性治疗选择。

结论

欧洲泌尿外科学会(EAU)建议采用两阶段评估来诊断前列腺切除术后尿失禁。对于术后早期和轻度尿失禁,推荐采用非侵入性治疗,即盆底肌肉训练和生物反馈。度洛西汀药物治疗与物理治疗联合使用时特别有效,二者协同作用可提高控尿率。对于手术治疗,植入人工尿道括约肌(AS-800)仍然是金标准。近年来,已经引入了几种微创治疗选择,成功率各不相同,但尚未超过人工括约肌的治疗效果。

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