Wilkins-Haug L, Freedman W
Denver General Hospital, CO 80204.
Prenat Diagn. 1991 Apr;11(4):227-33. doi: 10.1002/pd.1970110404.
Exencephaly as a precursor of anencephaly is well delineated in animal studies. In humans, a similar though unproven embryologic sequence is postulated. In the case reported, serial ultrasound studies allowed us to identify a 16-week human exencephalic fetus and observe the cephalic changes during its progression to a classic anencephalic appearance.
