El-Sadek M, El-Adl S, Abou-Kull M, Sakr S M
Pharmaceutical Chemistry Department, Faculty of Pharmacy, Zagazig University, Zagazig-Egypt.
Talanta. 1993 Apr;40(4):585-8. doi: 10.1016/0039-9140(93)80021-i.
A spectrophotometric determination of ketoprofen based upon oxime formation followed by charge transfer complexation with o-chloranil has been developed. Different variables affecting the complexation process have been studied. Beer's law is obeyed in the concentration range 10-80 microg/ml. The method has been successfully applied to the determination of ketoprofen in pure form and in pharmaceutical dosage forms in the presence of its impurities.
