Tabrizchi Mahmoud, Rouholahnejad Fereshteh
College of Chemistry, Isfahan University of Technology, Isfahan, Iran.
Talanta. 2006 Mar 15;69(1):87-90. doi: 10.1016/j.talanta.2005.09.016. Epub 2005 Oct 13.
This paper explains the effect of pressure on separation factor, resolving power (defined based on a single peak), and resolution (defined based on two adjacent peaks) in ion mobility spectrometry. IMS spectra were recorded at various pressures ranging from 39 hPa (29Torr) up to atmospheric pressure and various ion gates ranging from 50 to 225 micros. The results show that the IMS peaks shift perfectly linear with pressure so that separation factors remain unaffected by pressure. However, pressure has strong influence on resolving power and resolution. Reducing pressure at constant pulse width decreases the resolving power and resolution. On the other hand, the decrease in resolution can be compensated by shortening the ion pulse width since reducing pressure results in a higher ion current.
本文解释了压力对离子迁移谱中分离因子、分辨能力（基于单峰定义）和分辨率（基于两个相邻峰定义）的影响。在39 hPa（29托）至大气压的各种压力以及50至225微秒的各种离子门条件下记录了离子迁移谱。结果表明，离子迁移谱峰随压力呈完美线性移动，因此分离因子不受压力影响。然而，压力对分辨能力和分辨率有很大影响。在恒定脉冲宽度下降低压力会降低分辨能力和分辨率。另一方面，分辨率的降低可以通过缩短离子脉冲宽度来补偿，因为降低压力会导致更高的离子电流。
