[Chemical constituents from Polygonum capitatum and their antioxidation activities in vitro].

OBJECTIVE

To study the chemical constituents from Polygonum capitatum and their antioxidation activties in vitro.

METHODS

Compounds were isolated and purified by silica, polyamide and Sephadex LH-20 column chromatography. Their structures were identified by physicochemical properties and spectral analyses. The isolated compounds were screened with three antioxidation models in vitro.

RESULTS

Ten compounds were isolated and identified as galic acid (1), protocatechuic acid (2), progallin A (3), nimbecetin (4), quercetin (5), quercitroside (6), tetracosylferulate (7), quercetin-3-O-beta-D-glucoside (8), beta-deucosterol and beta-sitosterol (10). Compounds 1-6 from this plant showed antioxidation activities.

CONCLUSION

Compound 3 and 7 are isolated from this genus for the first time, compound 2, 4 and 9 are isolated from this plant for the first time, the pharmacological activities of the pure compounds from this plant are also reported firstly.