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丙泊酚镇静期间的心律失常。

Cardiac arrhythmia during propofol sedation.

作者信息

Douglas Robert J, Cadogan Mike

机构信息

Emergency Department, Royal Adelaide Hospital, North Terrace, Adelaide, South Australia.

出版信息

Emerg Med Australas. 2008 Oct;20(5):437-40. doi: 10.1111/j.1742-6723.2008.01126.x.

DOI:10.1111/j.1742-6723.2008.01126.x
PMID:18973642
Abstract

Recent articles have described the increasing frequency of use of propofol as a sedating agent in the ED, and praise the safety profile of propofol when used in this manner. We describe a patient who developed torsade de pointes followed by ventricular fibrillation while undergoing propofol sedation for closed reduction of a mid-shaft fracture of the tibia and fibula. Possible reasons for the event are discussed, and suggestions are made for areas of further research.

摘要

近期的文章描述了急诊科使用丙泊酚作为镇静剂的频率不断增加,并称赞了以这种方式使用丙泊酚时的安全性。我们描述了一名患者,在接受丙泊酚镇静以闭合复位胫腓骨中段骨折的过程中发生了尖端扭转型室速,随后发展为心室颤动。文中讨论了该事件可能的原因,并对进一步研究的领域提出了建议。

相似文献

1
Cardiac arrhythmia during propofol sedation.丙泊酚镇静期间的心律失常。
Emerg Med Australas. 2008 Oct;20(5):437-40. doi: 10.1111/j.1742-6723.2008.01126.x.
2
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Comparison of the effects of propofol and alfaxalone on the electrocardiogram of dogs, with particular reference to QT interval.丙泊酚和阿法沙龙对犬心电图的影响比较,特别关注QT间期。
Front Vet Sci. 2024 Jan 8;10:1330111. doi: 10.3389/fvets.2023.1330111. eCollection 2023.
2
Propofol in ICU Settings: Understanding and Managing Anti-Arrhythmic, Pro-Arrhythmic Effects, and Propofol Infusion Syndrome.重症监护病房环境中的丙泊酚:了解和处理抗心律失常、促心律失常作用及丙泊酚输注综合征
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3
Strong Early Phase Parasympathetic Inhibition Followed by Sympathetic Withdrawal During Propofol Induction: Temporal Response Assessed by Wavelet-Based Spectral Analysis and Photoplethysmography.
异丙酚诱导期间早期强烈的副交感神经抑制随后交感神经撤退:基于小波的频谱分析和光电容积描记法评估的时间反应
Front Physiol. 2021 Sep 13;12:705153. doi: 10.3389/fphys.2021.705153. eCollection 2021.
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Drugs Real World Outcomes. 2019 Sep;6(3):141-149. doi: 10.1007/s40801-019-00161-y.
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Propofol-associated QTc prolongation.丙泊酚相关的QTc间期延长。
Ther Adv Drug Saf. 2016 Jun;7(3):68-78. doi: 10.1177/2042098616641354. Epub 2016 Apr 1.
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Preliminary experience with a combination of dexmedetomidine and propofol infusions for diagnostic cardiac catheterization in children.右美托咪定与丙泊酚联合输注用于儿童诊断性心导管插入术的初步经验。
J Pediatr Pharmacol Ther. 2009 Apr;14(2):106-12. doi: 10.5863/1551-6776-14.2.106.
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