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[二氧化碳激光在声门肿瘤保守手术中的应用]

[Use of CO2 laser in conservative surgery of glottic tumors].

作者信息

Motta G, Villari G, Motta S, Ripa G, Cuzzocrea R

机构信息

Istituto di Clinica Otorinolaringoiatrica, II Facoltà di Medicina, dell'Università di Napoli.

出版信息

Acta Otorhinolaryngol Ital. 1991 Jan-Feb;11(1):25-34.

PMID:1897368
Abstract

The present work evaluates the results obtained in a group of 360 patients with laryngeal-glottic tumors (classification T1/T2-N0-M0) who, in the last 10 years, have undergone direct microlaryngoscopy surgery employing a CO2 Laser. In the T1 glottic carcinomas the neoplasm was limited to the vocal cord on one side or it involved the anterior commissure and, most likely, the vocal cord on the opposite side; in T2 glottic tumors the extension reached the hypoglottic region and/or the Morgagni ventricle and the false vocal cords on one or both sides but without compromising laryngeal motility. The five year healing rate for the T1 tumors proved to be 84.7% while it was 74% for the T2 forms. In 36 cases complications were found which can be broken down as follows: - limited local recurrences (13 patients) requiring subsequent direct microlaryngoscopy; - regional lymph node metastases (6 patients) without reproduction of the primary neoplasm; in general (5 of the 6 cases) these patients underwent lateral neck dissection; - spreading of the neoplastic process (17 cases) which made total laryngectomy with lateral neck dissection necessary; this procedure was performed in 15 cases. When these subsequent surgical procedures are also taken into account the percentage healing rises to 94.3% for T1 glottic tumors and to 84.9% for T2. Detailed analysis of the case study, comparison with the data found in the relative literature regarding patients treated with traditional techniques, a series of observations on the advantages and disadvantages inherent to the techniques employed have all led to the conclusion that the use of a CO2 laser in the treatment of laryngeal tumors gives excellent results in terms of prognosis. Moreover, this technique offers significant advantages over the traditional methods and constitutes a reliable technique for partial laryngectomies as long as the indications are accurately applied and the proper techniques used.

摘要

本研究评估了一组360例喉声门肿瘤患者(分类为T1/T2-N0-M0)的治疗结果,这些患者在过去10年中接受了二氧化碳激光直接显微喉镜手术。在T1声门癌中,肿瘤局限于一侧声带,或累及前联合,很可能还累及对侧声带;在T2声门肿瘤中,肿瘤扩展至声门下区域和/或 Morgagni 室以及一侧或双侧假声带,但未影响喉的活动度。T1肿瘤的五年治愈率为84.7%,而T2肿瘤为74%。发现36例并发症,具体如下: - 局限性局部复发(13例患者),需要后续直接显微喉镜检查; - 区域淋巴结转移(6例患者),未出现原发肿瘤复发;一般来说(6例中的5例),这些患者接受了侧颈清扫术; - 肿瘤扩散(17例),需要进行全喉切除术加侧颈清扫术;15例患者进行了此手术。如果将这些后续手术也考虑在内,T1声门肿瘤的治愈率升至94.3%,T2肿瘤升至84.9%。对病例研究的详细分析、与传统技术治疗患者的相关文献数据的比较、对所采用技术固有优缺点的一系列观察,均得出结论:在喉肿瘤治疗中使用二氧化碳激光在预后方面取得了优异的效果。此外,只要准确应用适应症并使用适当技术,该技术相对于传统方法具有显著优势,是一种可靠的部分喉切除术技术。

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