Dalrymple Kristy L, Zimmerman Mark
Warren Alpert Medical School of Brown University, Rhode Island Hospital, Providence, Rhode Island 02905, USA.
J Nerv Ment Dis. 2008 Aug;196(8):639-42. doi: 10.1097/NMD.0b013e318181353b.
Patients with comorbid major depressive disorder (MDD) and social anxiety disorder (SAD) demonstrate greater severity of symptoms and functional impairment compared with patients with either disorder alone. However, no known studies have examined what differentiates patients who do and do not want treatment for comorbid SAD in addition to MDD. The aim of the current study was to examine clinical characteristics (e.g., variables related to depression and social anxiety severity) of patients who did versus did not desire treatment for comorbid SAD. Results showed that patients who desired treatment for comorbid SAD reported a greater number of social fears and poorer work and current social functioning compared with patients who did not desire treatment for SAD. Work functioning and number of social fears remained significant after controlling for depression and overall illness severity. Results suggest that future treatments adapted for comorbid MDD and SAD perhaps should target work functioning and a broad range of social fears.
与仅患一种疾病的患者相比,患有共病性重度抑郁症(MDD)和社交焦虑症(SAD)的患者症状更严重,功能损害更明显。然而,尚无已知研究探讨是什么因素区分了除MDD外还患有共病性SAD且希望接受治疗的患者与不希望接受治疗的患者。本研究的目的是检查患有共病性SAD且希望接受治疗的患者与不希望接受治疗的患者的临床特征(例如,与抑郁和社交焦虑严重程度相关的变量)。结果显示,与不希望接受SAD治疗的患者相比,希望接受共病性SAD治疗的患者报告的社交恐惧更多,工作和当前社交功能更差。在控制了抑郁和总体疾病严重程度后,工作功能和社交恐惧数量仍然具有显著意义。结果表明,未来针对共病性MDD和SAD的治疗可能应针对工作功能和广泛的社交恐惧。