Galbusera Fabio, Bellini Chiara M, Costa Francesco, Assietti Roberto, Fornari Maurizio
LaBS, IRCCS Istituto Ortopedico Galeazzi, Milan, Italy.
J Neurosurg Spine. 2008 Nov;9(5):444-9. doi: 10.3171/SPI.2008.9.11.444.
Cervical instrumented fusion is currently performed using several fixation methods. In the present paper, the authors compare the following 4 implantation methods: a stand-alone cage, a cage supplemented by an anterior locking plate, a cage supplemented by an anterior dynamic plate, and a dynamic combined plate-cage device. METHODS Four finite element models of the C4-7 segments were built, each including a different instrumented fixation type at the C5-6 level. A compressive preload of 100 N combined with a pure moment of 2.5 Nm in flexion, extension, right lateral bending, and right axial rotation was applied to the 4 models. The segmental principal ranges of motion and the load shared by the interbody cage were obtained for each simulation.
The stand-alone cage showed the lowest stabilization capability among the 4 configurations investigated, but it was still significant. The cage supplemented by the locking plate was very stiff in all directions. The 2 dynamic plate configurations reduced flexibility in all directions compared with the intact case, but they left significant mobility in the implanted segment. These configurations were able to share a significant part of the load (up to 40% for the combined plate-cage) through the posterior cage. The highest risk of subsidence was obtained with the model of the stand-alone cage.
Noticeable differences in the results were detected for the 4 configurations. The actual clinical relevance of these differences, currently considered not of critical importance, should be investigated by randomized clinical trials.
颈椎器械融合术目前采用多种固定方法。在本文中,作者比较了以下4种植入方法:单独使用椎间融合器、椎间融合器辅以前路锁定钢板、椎间融合器辅以前路动力钢板以及动力组合钢板-椎间融合器装置。方法:构建C4 - 7节段的4个有限元模型,每个模型在C5 - 6水平采用不同的器械固定类型。对这4个模型施加100 N的压缩预载荷,并在屈曲、伸展、右侧侧弯和右侧轴向旋转时施加2.5 Nm的纯力矩。每次模拟均获取节段的主要活动范围以及椎间融合器分担的载荷。
在所研究的4种构型中,单独使用椎间融合器的稳定能力最低,但仍具有显著性。辅以锁定钢板的椎间融合器在各个方向都非常僵硬。与完整情况相比,两种动力钢板构型在各个方向上均降低了灵活性,但在植入节段仍保留了显著的活动度。这些构型能够通过后路椎间融合器分担很大一部分载荷(组合钢板-椎间融合器可达40%)。单独使用椎间融合器的模型下沉风险最高。
4种构型的结果存在显著差异。目前认为这些差异在临床实际中并不关键,但其实际临床相关性应通过随机临床试验进行研究。