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中重度创伤性脑损伤10年后的功能结局及健康相关生活质量

Functional outcome and health-related quality of life 10 years after moderate-to-severe traumatic brain injury.

作者信息

Andelic N, Hammergren N, Bautz-Holter E, Sveen U, Brunborg C, Røe C

机构信息

Department of Physical Medicine and Rehabilitation, Ulleval University Hospital, University of Oslo, Oslo, Norway.

出版信息

Acta Neurol Scand. 2009 Jul;120(1):16-23. doi: 10.1111/j.1600-0404.2008.01116.x. Epub 2008 Oct 23.

Abstract

OBJECTIVES

To describe the functional outcome and health-related quality of life (HRQL) 10 years after moderate-to-severe traumatic brain injury (TBI).

MATERIAL AND METHODS

A retrospective, population-based study of 62 survivors of working-age with moderate-to-severe TBI injured in 1995/1996, and hospitalized at the Trauma Referral Center in Eastern Norway. Functional status was measured by the Glasgow Outcome Scale-Extended (GOS-E). HRQL was assessed by the SF-36 questionnaire.

RESULTS

The mean current-age was 40.8 years. The frequency of epilepsy was 19% and the depression rate 31%. A majority had good recovery (48%) or moderate disability (44%). Employment rate was 58%. Functional and employment status were associated with initial injury severity in contrast to HRQL. Study patients had significantly lower scores in all SF-36 dimensions when compared with the general Norwegian population.

CONCLUSION

At 10-years follow-up, our study population is still in their most productive years and affected domains should be considered in long-term follow-up and intervention programs.

摘要

目的

描述中重度创伤性脑损伤(TBI)10年后的功能转归及健康相关生活质量(HRQL)。

材料与方法

一项基于人群的回顾性研究,研究对象为1995/1996年受伤、在挪威东部创伤转诊中心住院治疗的62名工作年龄的中重度TBI幸存者。功能状态采用扩展格拉斯哥预后量表(GOS-E)进行测量。HRQL通过SF-36问卷进行评估。

结果

目前的平均年龄为40.8岁。癫痫发生率为19%,抑郁率为31%。大多数人恢复良好(48%)或有中度残疾(44%)。就业率为58%。与HRQL不同,功能和就业状况与初始损伤严重程度相关。与挪威普通人群相比,研究患者在所有SF-36维度上的得分均显著较低。

结论

在10年随访时,我们的研究人群仍处于生产力最高的年龄段,在长期随访和干预项目中应考虑受影响的领域。

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