Kröger Liisa, Kotaniemi Kaisu, Jääskeläinen Jarmo
Department of Paediatrics, Kuopio University Hospital, Kuopio, Finland.
Acta Paediatr. 2009 Mar;98(3):584-5. doi: 10.1111/j.1651-2227.2008.01091.x. Epub 2008 Oct 23.
The adverse effects of corticosteroids are well-known and occur more frequently when corticosteroids are used perorally or intravenously. The management of uveitis, which normally consists of topical corticosteroids and mydriates, can be challenging. We report a case in which continuous use of topical corticosteroids resulted in adrenal insufficiency and obesity.
When topical corticosteroids are used over longer periods, hypophysis-pituitary-adrenal (HPA) function should be carefully monitored.
皮质类固醇的不良反应众所周知，且当口服或静脉使用皮质类固醇时更常发生。葡萄膜炎的治疗通常包括局部使用皮质类固醇和散瞳剂，这可能具有挑战性。我们报告一例连续使用局部皮质类固醇导致肾上腺功能不全和肥胖的病例。
当长期使用局部皮质类固醇时，应仔细监测垂体-垂体-肾上腺（HPA）功能。
