Carrillo T, Rodriguez de Castro F, Cuevas M, Diaz F, Cabrera P
Section of Allergy and Respiratory Diseases, Hospital Ntra Sra del Pino, University of Las Palmas, Spain.
Allergy. 1991 May;46(4):241-4. doi: 10.1111/j.1398-9995.1991.tb00580.x.
Tobacco smoking is associated with increased prevalence of various diseases. In this study, we have used an indirect enzyme-linked immunosorbent assay (ELISA) to investigate the specific IgG response to pigeon serum and its relationship to tobacco smoking. In a large group of pigeon fanciers the development of pigeon breeder's disease and some of the clinical features were also investigated. We found a sensitization rate of 31.9%, a lower degree than that found by other authors, in spite of using a less specific antigen. We also found that fanciers who are current cigarette smokers had significantly lower levels of IgG antibody to pigeon serum (P less than 0.001). Finally, 11.9% of the population had chronic bronchitis as their only manifestation of possible pigeon-related disease. 19.6% of the sensitized fanciers had chronic bronchitis, were non-smokers and had no other risk factor for developing chronic bronchitis.
吸烟与多种疾病患病率的增加有关。在本研究中，我们使用间接酶联免疫吸附测定（ELISA）来研究对鸽血清的特异性IgG反应及其与吸烟的关系。在一大群养鸽人中，还调查了养鸽者病的发生情况和一些临床特征。尽管使用的抗原特异性较低，但我们发现致敏率为31.9%，低于其他作者的发现。我们还发现，目前吸烟的养鸽者对鸽血清的IgG抗体水平显著较低（P小于0.001）。最后，11.9%的人群患有慢性支气管炎，这是可能的鸽相关疾病的唯一表现。19.6%的致敏养鸽者患有慢性支气管炎，他们不吸烟，也没有其他患慢性支气管炎的危险因素。
