Chen Chung-Yao, Chen Chia-Ling, Hsu Steele Chih-Chin, Chou Shih-Wei, Wang Kun-Chung
Department of Physical Medicine and Rehabilitation, Chang Gung Memorial Hospital, Keelung, Taiwan.
Arch Phys Med Rehabil. 2008 Dec;89(12):2258-64. doi: 10.1016/j.apmr.2008.05.019. Epub 2008 Nov 1.
To determine the effects of magnetic knee wrap on isokinetic quadriceps strength in patients with painful knee osteoarthritis (OA).
Randomized, double-blinded, placebo-controlled and before-after trial.
Rehabilitation clinic in a tertiary hospital.
Eligible patients (N=50) (mean age+/-SD, 66.0+/-8.6 y) with mild to moderate knee OA were recruited from the outpatient department and 37 (74%) completed the trial. Only 3 (6%) withdrew due to study-related adverse effects.
Wearing the active (n=24) or sham (n=26) magnetic knee wrap for 12 weeks.
The primary outcome measure was isokinetic quadriceps strength. Secondary outcome measures included the Health Assessment Questionnaire Disability Index (HAQ-DI) and the Health Assessment Questionnaire (HAQ) Pain Scale.
Using intention-to-treat analyses, the peak isokinetic quadriceps strength increased significantly in the treated leg at 30 degrees/s (P=.007) and 60 degrees/s (P=.022) after wearing the magnetic knee wrap. Compared with baseline, the median strength increase for the treated leg in the study group significantly exceeded that in the control group at week 4 (.05 Nm/kg vs -.09 Nm/kg at 60 degrees/s, P=.038) and week 12 (30 degrees/s, .09 Nm/kg vs .04 Nm/kg, P=.044; 60 degrees/s, .17 Nm/kg vs .02 Nm/kg, P=.031). The HAQ-DI and HAQ Pain Scales improved significantly in both groups. Compared with baseline, the improvement at week 12 in terms of the HAQ-DI in the study group significantly exceeded that in the control group.
Magnetic knee wrap may significantly facilitate isokinetic quadriceps strength in patients with mild to moderate knee OA.
确定磁性护膝对疼痛性膝骨关节炎（OA）患者等速股四头肌力量的影响。
随机、双盲、安慰剂对照及前后对照试验。
一家三级医院的康复诊所。
从门诊招募了符合条件的轻度至中度膝OA患者（N = 50）（平均年龄±标准差，66.0±8.6岁），37名（74%）完成了试验。仅3名（6%）因与研究相关的不良反应退出。
佩戴活性（n = 24）或假（n = 26）磁性护膝12周。
主要结局指标为等速股四头肌力量。次要结局指标包括健康评估问卷残疾指数（HAQ - DI）和健康评估问卷（HAQ）疼痛量表。
采用意向性分析，佩戴磁性护膝后，治疗腿在30度/秒（P = 0.007）和60度/秒（P = 0.022）时等速股四头肌力量峰值显著增加。与基线相比，研究组治疗腿的力量中位数增加在第4周（60度/秒时，0.05 Nm/kg对 - 0.09 Nm/kg，P = 0.038）和第12周（30度/秒时，0.09 Nm/kg对0.04 Nm/kg，P = 0.044；60度/秒时，0.17 Nm/kg对0.02 Nm/kg，P = 0.031）显著超过对照组。两组的HAQ - DI和HAQ疼痛量表均显著改善。与基线相比，研究组在第12周时HAQ - DI的改善显著超过对照组。
磁性护膝可能显著促进轻度至中度膝OA患者的等速股四头肌力量。
