Mathur P P, Chattopadhyay S
School of Life Sciences, Pondicherry University, India.
Andrologia. 1991 Jan-Feb;23(1):49-51. doi: 10.1111/j.1439-0272.1991.tb02496.x.
The effect of alteration of central turnover of monoamines on the intratesticular mechanisms in the testis of rats was studied after REM sleep-deprivation. The reduction in the weights of ventral prostate, seminal vesicles and decreased activity of beta-glucuronidase in kidney reflected decreased availability of testosterone to the target organs. Decreased activities of lysosomal enzymes, acid phosphatase and beta-glucuronidase were associated with a decreased steroidogenic activity in the testis. The active mediation of lysosomal enzymes in the testicular function under altered condition was indicated.
在快速眼动睡眠剥夺后，研究了单胺类物质中枢周转率的改变对大鼠睾丸内机制的影响。腹侧前列腺和精囊重量减轻以及肾脏中β-葡萄糖醛酸酶活性降低，反映了靶器官可利用的睾酮减少。溶酶体酶、酸性磷酸酶和β-葡萄糖醛酸酶活性降低与睾丸中类固醇生成活性降低有关。这表明在改变的条件下，溶酶体酶对睾丸功能有积极的调节作用。
