Mathur P P, Chattopadhyay S
Andrologia. 1985 May-Jun;17(3):297-300. doi: 10.1111/j.1439-0272.1985.tb01007.x.
The effect of loss of integrity of seminiferous tubules on intracellular mechanisms in the testis of rats was studied after intratesticular administration of homologous serum. The increased weights of ventral prostate, seminal vesicles and increased activity of beta glucuronidase in kidney reflected an increased availability of testosterone to the target organs. The pulse labelling of 32P in the nucleic acid fraction of testis was significantly increased. The concentration of testicular DNA was increased while the ascorbic acid was slightly decreased. Activities of the lysosomal enzymes, acid phosphatase and beta glucuronidase increased. The involvement of lysosomal enzymes in the testicular function under altered condition was indicated.
在大鼠睾丸内注射同源血清后，研究了曲细精管完整性丧失对大鼠睾丸细胞内机制的影响。腹侧前列腺和精囊重量增加，肾脏中β-葡萄糖醛酸酶活性增强，这反映了靶器官可利用的睾酮增加。睾丸核酸部分的³²P脉冲标记显著增加。睾丸DNA浓度升高，而抗坏血酸略有下降。溶酶体酶、酸性磷酸酶和β-葡萄糖醛酸酶的活性增加。这表明在改变的条件下，溶酶体酶参与了睾丸功能。
