Gruzman A B, Khapiĭ Kh Kh
Anesteziol Reanimatol. 1991 May-Jun(3):17-21.
Glucose release and lactate uptake by the brain during coma is discussed. A hypothesis of autonomous gluconeogenesis in the brain is suggested. To substantiate the hypothesis use is made of the literature data on the presence in the brain of stimuli, and its provision with substrates and gluconeogenetic enzyme apparatus. Special attention is paid to the problem of gluconeogenesis energy supply during hypoxia, using proton or sodium potentials.
讨论了昏迷期间大脑对葡萄糖的释放和对乳酸的摄取。提出了大脑中自主糖异生的假说。为证实这一假说，利用了有关大脑中刺激物的存在、其底物供应和糖异生酶装置的文献数据。特别关注了在缺氧期间利用质子或钠电位进行糖异生能量供应的问题。
