Rajasekaran Sanguthevar, Balla Sudha, Gradie Patrick, Gryk Michael R, Kadaveru Krishna, Kundeti Vamsi, Maciejewski Mark W, Mi Tian, Rubino Nicholas, Vyas Jay, Schiller Martin R
Department of Computer Science and Engineering, University of Connecticut, Storrs, CT 06029-2155, USA.
Nucleic Acids Res. 2009 Jan;37(Database issue):D185-90. doi: 10.1093/nar/gkn865. Epub 2008 Oct 31.
Minimotif Miner (MnM) consists of a minimotif database and a web-based application that enables prediction of motif-based functions in user-supplied protein queries. We have revised MnM by expanding the database more than 10-fold to approximately 5000 motifs and standardized the motif function definitions. The web-application user interface has been redeveloped with new features including improved navigation, screencast-driven help, support for alias names and expanded SNP analysis. A sample analysis of prion shows how MnM 2 can be used. Weblink: http://mnm.engr.uconn.edu, weblink for version 1 is http://sms.engr.uconn.edu.
最小基序挖掘器(MnM)由一个最小基序数据库和一个基于网络的应用程序组成,该应用程序能够预测用户提供的蛋白质查询中基于基序的功能。我们对MnM进行了修订,将数据库扩展了10倍以上,达到约5000个基序,并对基序功能定义进行了标准化。网络应用程序的用户界面已重新开发,具有新功能,包括改进的导航、屏幕录像驱动的帮助、对别名的支持以及扩展的单核苷酸多态性(SNP)分析。对朊病毒的样本分析展示了如何使用MnM 2。网址:http://mnm.engr.uconn.edu,版本1的网址是http://sms.engr.uconn.edu。