Sebastian M, Schad A, Schadmand-Fischer S, Post F, Meier S, Springer E, Makowski J, Taube C, Wiewrodt R, Fischer B, Buhl R
III. Medizinische Klinik und Poliklinik, Johannes Gutenberg-Universität, Langenbeckstrasse 1, 55101 Mainz.
Internist (Berl). 2009 Jan;50(1):91-4. doi: 10.1007/s00108-008-2239-0.
Even people which have never smoked can develop lung cancer. In this population a mutation in the exons 19-21 of the Epidermal Growth Factor Receptor (EGFR) can be detected. For this patient group targeted therapies with EGFR tyrosinkinase inhibitors are available. In this case report we describe a 37 year old non-smoker who developed a non-small cell lung cancer. Following therapy with Erlotinib a partial response could be achieved.
即使从不吸烟的人也可能患肺癌。在这一人群中，可以检测到表皮生长因子受体（EGFR）外显子19 - 21的突变。对于该患者群体，有针对EGFR酪氨酸激酶抑制剂的靶向治疗方法。在本病例报告中，我们描述了一名37岁的非吸烟者，他患上了非小细胞肺癌。使用厄洛替尼治疗后，病情取得了部分缓解。
