Wassarman Paul M, Litscher Eveline S
Department of Molecular, Cell and Developmental Biology, Mount Sinai School of Medicine, New York, NY, USA.
Methods Mol Biol. 2008;475:99-113. doi: 10.1007/978-1-59745-250-2_6.
Successful completion of fertilization in mammals is dependent on three membrane fusion events. These are (1) the acrosome reaction of sperm, (2) the fusion of sperm and egg plasma membranes to form a zygote, and (3) the cortical reaction of fertilized eggs. Extensive research into the molecular basis of each of these events has identified candidate proteins and factors involved in fusion of membranes during the mammalian fertilization process. Some of this information is provided here.
哺乳动物受精的成功完成依赖于三个膜融合事件。这些事件包括：（1）精子的顶体反应；（2）精子与卵质膜融合形成受精卵；（3）受精卵的皮质反应。对这些事件各自分子基础的广泛研究已经确定了参与哺乳动物受精过程中膜融合的候选蛋白质和因子。这里提供了其中一些信息。
