Pandya Vivek B, Conway R Max, Taylor Simon F
University of Sydney, Sydney, NSW, Australia.
Clin Exp Ophthalmol. 2008 Oct;36(7):672-4. doi: 10.1111/j.1442-9071.2008.01858.x.
Primary cutaneous lymphoma represents a distinct clinical entity within the spectrum of haematological malignancy. A case of primary cutaneous B cell lymphoma is reported, presenting in an 87-year-old female with a 2-year history of intermittent swelling and discolouration of the right upper and lower eyelids, in the absence of systemic symptoms. Histopathological examination of an incision biopsy revealed a lymphoid infiltrate in the dermis with immunophenotypic features of B cell lymphoma. Staging investigations confirmed the absence of systemic disease. Treatment with oral chemotherapy was undertaken with a good response. Ophthalmologists should include primary cutaneous lymphoma in the differential diagnosis of recurrent eyelid swelling.
原发性皮肤淋巴瘤是血液系统恶性肿瘤谱系中的一种独特临床实体。本文报告了一例原发性皮肤B细胞淋巴瘤病例,患者为一名87岁女性,右上睑和右下睑间歇性肿胀和变色2年,无全身症状。切口活检的组织病理学检查显示真皮有淋巴细胞浸润,具有B细胞淋巴瘤的免疫表型特征。分期检查证实无全身疾病。采用口服化疗治疗,反应良好。眼科医生在复发性眼睑肿胀的鉴别诊断中应考虑原发性皮肤淋巴瘤。