子宫内膜癌治疗后女性的泌尿系统症状及其对生活质量的影响。
Urinary symptoms and impact on quality of life in women after treatment for endometrial cancer.
作者信息
Erekson E A, Sung V W, DiSilvestro P A, Myers D L
机构信息
Division of Urogynecology and Pelvic Reconstructive Surgery, Alpert Medical School at Brown University, Women and Infants' Hospital of Rhode Island, 695 Eddy St, Ste. 12, Providence, RI 02903, USA.
出版信息
Int Urogynecol J Pelvic Floor Dysfunct. 2009 Feb;20(2):159-63. doi: 10.1007/s00192-008-0755-z. Epub 2008 Nov 5.
Abstract
The primary objective of our study is to describe urinary symptoms in women treated for endometrial cancer. We performed a cross-sectional survey of women who had undergone surgical treatment for endometrial cancer. Three validated questionnaires were utilized: the Sandvik Severity Index, the Urinary Distress Inventory-6 (UDI-6), and Incontinence Impact Questionaire-7 (IIQ-7). Our study included 70 women treated for endometrial cancer; 35.7% (25/70) of women reported adjuvant radiation therapy after surgical staging. Urinary incontinence was reported in over 80% of women. Mean UDI-6 and IIQ-7 scores for women treated with adjuvant radiation therapy were higher compared to women with no adjuvant radiation therapy [47(+/-26.8) vs. 35.6(+/-21.7; p = 0.05)] and [24.4(+/-28.5) vs. 8.1(+/-16.4; p = 0.004)], respectively. Treatment with adjuvant radiation therapy was associated with more severe incontinence symptoms and impact on quality of life.
摘要
我们研究的主要目的是描述接受子宫内膜癌治疗的女性的泌尿系统症状。我们对接受过子宫内膜癌手术治疗的女性进行了横断面调查。使用了三份经过验证的问卷：桑德维克严重程度指数、泌尿困扰量表-6（UDI-6）和尿失禁影响问卷-7（IIQ-7）。我们的研究纳入了70名接受子宫内膜癌治疗的女性；35.7%（25/70）的女性在手术分期后报告接受了辅助放疗。超过80%的女性报告有尿失禁。接受辅助放疗的女性的平均UDI-6和IIQ-7得分高于未接受辅助放疗的女性，分别为[47（±26.8）对35.6（±21.7；p = 0.05）]和[24.4（±28.5）对8.1（±16.4；p = 0.004）]。辅助放疗与更严重的尿失禁症状以及对生活质量的影响相关。
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