Schneider Frank, Althaus Astrid, Backes Volker, Dodel Richard
Department of Psychiatry and Psychotherapy, RWTH Aachen, Pauwelsstrasse 30, Aachen, Germany.
Eur Arch Psychiatry Clin Neurosci. 2008 Nov;258 Suppl 5:55-9. doi: 10.1007/s00406-008-5012-4.
Parkinson's disease (PD) is a neurodegenerative disorder which is often reduced to a mere dysfunction of motor performance. Non-motor symptoms, however, are frequent impairments in PD and result in a major impact on the patients and their caregivers. The major neuropsychiatric comorbidities depression, anxiety, and psychotic symptoms are briefly discussed. Additionally, a brief outlook on deep brain stimulation and its effect on psychiatric symptoms is provided. Several studies did show that neuropsychiatric symptoms are underdiagnosed and consecutively treated inadequately. All in all more attention should be directed to the detection and treatment of psychiatric symptoms in PD patients in routine clinical settings.
帕金森病(PD)是一种神经退行性疾病,通常被简化为仅仅是运动功能障碍。然而,非运动症状在帕金森病中很常见,会对患者及其照顾者产生重大影响。本文简要讨论了主要的神经精神合并症,即抑郁、焦虑和精神症状。此外,还简要展望了深部脑刺激及其对精神症状的影响。多项研究表明,神经精神症状的诊断不足,后续治疗也不充分。总之,在常规临床环境中,应更加关注帕金森病患者精神症状的检测和治疗。