Gluer C C
Medizinische Phys., Univ. Schleswig-Holstein, Kiel, Germany.
IEEE Trans Ultrason Ferroelectr Freq Control. 2008 Jul;55(7):1524-8. doi: 10.1109/TUFFC.2008.828.
Quantitative ultrasound (QUS) methods have strong power to predict osteoporotic fractures, but they are also very relevant for the assessment of bone quality. A representative sample of recent studies addressing these topics can be found in this special issue. Further pursuit of these methods will establish micro-QUS imaging methods as tools for measuring specific aspects of bone quality. Once this is achieved, we will be able to link such data to the clinical QUS methods used in vivo to determine which aspects of bone quality cause QUS to be a predictor of fracture risk that is independent of bone mineral density (BMD). Potentially this could lead to the development of a new generation of QUS devices for improved and expanded clinical assessment. Good quality of basic science work will thus lead to good quality of clinical patient examinations on the basis of a more detailed assessment of bone quality.
定量超声（QUS）方法在预测骨质疏松性骨折方面具有强大的能力，而且它们对于骨质量的评估也非常重要。本期特刊中有一系列近期针对这些主题的代表性研究。对这些方法的进一步探索将确立微QUS成像方法作为测量骨质量特定方面的工具。一旦实现这一点，我们将能够将此类数据与体内使用的临床QUS方法联系起来，以确定骨质量的哪些方面导致QUS成为独立于骨密度（BMD）的骨折风险预测指标。这可能会推动新一代QUS设备的开发，以改进和扩展临床评估。因此，高质量的基础科学工作将在对骨质量进行更详细评估的基础上带来高质量的临床患者检查。
