活化蛋白C抵抗、凝血因子V莱顿突变与血栓形成风险评估
Activated protein C resistance, factor V Leiden and assessment of thrombotic risk.
作者信息
Gilmore R, Doyle M, Holden F, White B, O'Donnell J
机构信息
National Centre for Hereditary Coagulation Disorders, St James's Hospital, James's Street, Dublin.
出版信息
Ir Med J. 2008 Sep;101(8):256-7.
Venous thromboembolism comprises deep vein thrombosis (DVT) and pulmonary embolism (PE). Acute venous thromboembolism (VTE) is a serious and potentially fatal disorder which often complicates the course of hospitalized patients, but also affects ambulatory and otherwise healthy people. The annual incidence of venous thromboembolism is 1 to 2 cases per 1000 person and the risk of the disorder rises exponentially with age, from an annual rate of less than 5 per 100,000 children to greater than 400 per 100,000 adults older than 80 years.
静脉血栓栓塞症包括深静脉血栓形成（DVT）和肺栓塞（PE）。急性静脉血栓栓塞症（VTE）是一种严重且可能致命的疾病，它常常使住院患者的病程复杂化，但也会影响门诊患者及其他健康人群。静脉血栓栓塞症的年发病率为每1000人中有1至2例，并且该疾病的风险随年龄呈指数级上升，从每年每10万名儿童中少于5例增至每年每10万名80岁以上成年人中超过400例。
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