Agrawal Dinesh Kumar, Saikia Dharmendra, Tiwari Richa, Ojha Shweta, Shanker Karuna, Kumar Jonnala Kotesh, Gupta Anil Kumar, Tandon Sudeep, Negi Arvind Singh, Khanuja Suman Preet
Analytical Chemistry Division, Central Institute of Medicinal and Aromatic Plants (CIMAP-CSIR), Lucknow, India.
Planta Med. 2008 Dec;74(15):1828-31. doi: 10.1055/s-0028-1088335. Epub 2008 Nov 7.
Demethoxycurcumin, isolated from the rhizomes of Curcuma longa, was found to possess antitubercular activity against Mycobacterium tuberculosis H (37)Rv strain at 200 microg/mL. Derivatisation of this active principle yielded a potent agent 6, exhibiting considerable activity with a minimum inhibitory concentration (MIC) value of 7.8 microg/mL. H (37)Rv:Mycobacterium tuberculosis H (37)Rv strain MIC:minimum inhibitory concentration.
从姜黄根茎中分离出的去甲氧基姜黄素，被发现对结核分枝杆菌H（37）Rv菌株在200微克/毫升浓度下具有抗结核活性。这种活性成分的衍生化产生了一种强效药剂6，其表现出相当强的活性，最低抑菌浓度（MIC）值为7.8微克/毫升。H（37）Rv：结核分枝杆菌H（37）Rv菌株；MIC：最低抑菌浓度
