Sun Lian-li, Luan Ming, Zhu Wei, Gao Shuai, Zhang Qian-lan, Xu Chan-juan, Lu Xiang-hong, Xu Xiang-dong, Tian Jing-Kui, Zhang Lin
The Key Laboratory of Biomedical Engineering, Ministry of Education, China, Department of Biomedical Engineering, Zhejiang University, Hangzhou 310027, China.
Chem Pharm Bull (Tokyo). 2013;61(8):873-6. doi: 10.1248/cpb.c13-00216. Epub 2013 May 24.
Two new compounds with five known compounds have been isolated from EtOH extract of the seeds of Nigella glandulifera. On the basis of their spectroscopic and chemical evidence, the new compounds were elucidated as methoxynigeglanine (1) and 6-methoxythymol-3-O-β-D-glucopyranoside (4). Compounds 1-4 showed moderate antitubercular activity against Mycobacterium tuberculosis strain H37Rv with minimal inhibitory concentration (MIC) values of 32-250 µg/mL.
从腺毛黑种草种子的乙醇提取物中分离出了两种新化合物和五种已知化合物。基于它们的光谱和化学证据，新化合物被鉴定为甲氧基黑种草胺（1）和6-甲氧基百里酚-3-O-β-D-葡萄糖苷（4）。化合物1-4对结核分枝杆菌H37Rv菌株显示出中等抗结核活性，最低抑菌浓度（MIC）值为32-250μg/mL。
