Polat Uri
Goldschleger Eye Research Institute, Tel Aviv University, Sheba Medical Center, Ramat Gan, Tel Hashomer, 52621 Israel.
Restor Neurol Neurosci. 2008;26(4-5):413-24.
Amblyopia is a reduction of visual functions that cannot be attributed directly to the effect of any structural abnormality of the eye or the posterior visual pathway. It is caused by abnormal binocular visual experience early in life, during the 'critical period' that prevents normal development of the visual system. It is widely accepted that therapy can only be effective during the critical period, and that it is not administered after the first decade of life. Here we provide an overview describing a recent finding of visual abnormalities in amblyopia and propose a treatment that we developed based on this finding. Both previous and new results that are presented here clearly show the success of the structured method, targeted at the specific deficiencies in amblyopia, to improve vision in children and adults. Our results suggest that the training was successful in rejuvenating the visual system and in restoring lost development from the sensory obstacle period. It is possible that the perceptual learning method used here can be applied to other sensory and non-sensory brain modules suffering from developmental problems.
弱视是一种视觉功能减退,不能直接归因于眼睛或视觉后通路的任何结构异常。它是由生命早期在“关键期”的异常双眼视觉体验引起的,这种体验会阻止视觉系统的正常发育。人们普遍认为,治疗只能在关键期有效,且在生命的第一个十年之后就不再进行治疗。在此,我们提供一篇综述,描述弱视中视觉异常的最新发现,并提出基于这一发现开发的一种治疗方法。本文展示的既往及新结果均清楚表明,针对弱视的特定缺陷的结构化方法在改善儿童和成人视力方面取得了成功。我们的结果表明,该训练成功地使视觉系统恢复活力,并从感觉障碍期恢复了丧失的发育。这里使用的知觉学习方法有可能应用于其他存在发育问题的感觉和非感觉脑模块。
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