Jia Wuli, Lan Fangfang, Zhao Xin, Lu Zhong-Lin, Huang Chang-Bing, Zhao Wuxiao, Li Min
School of Education Science, Huaiyin Normal University, 111 Changjiang West Road, Huaian 223300, China.
Center for Optometry and Visual Science, Department of Optometry and Ophthalmology, The People's Hospital of Guangxi Zhuang Autonomous Region, 6 Taoyuan Road, Qingxiu Dist., Nanning 530021, China.
Vision Res. 2018 Nov;152:74-83. doi: 10.1016/j.visres.2017.02.008. Epub 2017 Jun 27.
Intensive monocular perceptual learning can improve visual acuity, contrast sensitivity, and vernier acuity in the amblyopic eye in adults with amblyopia. It is however not clear how much monocular training can enhance binocular visual functions. In the current study, we aimed to evaluate effects of monocular training on a variety of binocular functions. Nineteen anisometropic amblyopes (18.5±1.26yrs, mean±s.e.) were trained in a grating contrast detection task near each individual's cutoff spatial frequency for 6-10days (630 trials/day). Visual acuity, stereoacuity, monocular and binocular contrast sensitivity functions (CSF), binocular phase combination and binocular rivalry were tested before and after training. Although monocular training can improve visual acuity and contrast sensitivity and eye dominance of the amblyopic eye, the magnitudes of improvements did not correlate with each other; the impact of monocular training on binocular phase combination was not significant. The results strongly suggest that structured monocular and binocular training is needed to fully recover deficient visual functions in anisometropic amblyopia.
强化单眼感知学习可以提高成人弱视患者弱视眼的视力、对比敏感度和游标视力。然而，目前尚不清楚单眼训练能在多大程度上增强双眼视觉功能。在本研究中，我们旨在评估单眼训练对多种双眼功能的影响。19名屈光参差性弱视患者（18.5±1.26岁，均值±标准误）在接近各自截止空间频率的光栅对比度检测任务中接受了6至10天的训练（每天630次试验）。在训练前后分别测试了视力、立体视锐度、单眼和双眼对比敏感度函数（CSF）、双眼相位组合和双眼竞争。虽然单眼训练可以提高弱视眼的视力、对比敏感度和眼优势，但改善程度之间并无相关性；单眼训练对双眼相位组合的影响并不显著。结果强烈表明，需要进行有组织的单眼和双眼训练，才能使屈光参差性弱视患者完全恢复受损的视觉功能。
