Polat Uri, Ma-Naim Tova, Spierer Abraham
Goldschleger Eye Research Institute, Tel-Aviv University, Sheba Medical Center, 52621 Tel Hashomer, Israel.
Vision Res. 2009 Oct;49(21):2599-603. doi: 10.1016/j.visres.2009.07.008. Epub 2009 Jul 19.
Recent studies have shown that perceptual learning has the potential to treat amblyopia. In this study we tested whether a recent perceptual learning technique that improved visual functions in adults can be applied to improve the vision of children after the conventional treatment of patching has failed. A prospective clinical pilot study was carried out in children who were non-compliant with patching or in whom patching had failed despite good compliance. Each child underwent a complete eye examination before and after treatment. The treatment was based on a perceptual learning technique that was similar to the adult study [Polat, U., Ma-Naim, T., Belkin, M., & Sagi, D. (2004). Improving vision in adult amblyopia by perceptual learning. Proceedings of the National Academy of Sciences of the United States of America, 101(17), 6692-6697]. Between blocks, children played a computer game to engage and maintain their attention in order to increase compliance. Each child received two treatment sessions a week, with a total of not more than 40 sessions. Each session lasted for about 1h and included a total practice time of about 30min. The age of the children (n=5) was between 7 and 8years (mean 7.3years). For the whole group, the average improvement in visual acuity was 1.5 Snellen lines or 2.12 ETDRS lines. The training improved the contrast sensitivity, which reached the normal range after treatment. Thus, the perceptual learning technique can be successfully used to treat children with amblyopia even after the conventional treatment of patching fails.
近期研究表明，知觉学习具有治疗弱视的潜力。在本研究中，我们测试了一种最近的知觉学习技术，该技术能改善成年人的视觉功能，在传统遮盖治疗失败后，是否可应用于提高儿童的视力。对不依从遮盖治疗或虽依从但遮盖治疗失败的儿童进行了一项前瞻性临床试点研究。每个孩子在治疗前后都接受了全面的眼部检查。治疗基于一种与成人研究[波拉特，U.，马-奈姆，T.，贝尔金，M.，&萨吉，D.（2004年）。通过知觉学习改善成人弱视视力。美国国家科学院院刊，101(17)，6692 - 6697]中相似的知觉学习技术。在各训练单元之间，孩子们玩电脑游戏以吸引并保持他们的注意力，从而提高依从性。每个孩子每周接受两次治疗，总共不超过40次。每次治疗持续约1小时，包括总计约30分钟的练习时间。孩子们（n = 5）的年龄在7至8岁之间（平均7.3岁）。对于整个组，视力平均提高了1.5斯内伦视力行或2.12 ETDRS视力行。训练提高了对比敏感度，治疗后达到了正常范围。因此，即使在传统遮盖治疗失败后，知觉学习技术也可成功用于治疗弱视儿童。
