Long Brian R, Heller Martin, Beech Jason P, Linke Heiner, Bruus Henrik, Tegenfeldt Jonas O
Materials Science Institute, University of Oregon, Eugene, Oregon 97403-1274, USA.
Phys Rev E Stat Nonlin Soft Matter Phys. 2008 Oct;78(4 Pt 2):046304. doi: 10.1103/PhysRevE.78.046304. Epub 2008 Oct 2.
Deterministic lateral displacement (DLD) devices separate micrometer-scale particles in solution based on their size using a laminar microfluidic flow in an array of obstacles. We investigate array geometries with rational row-shift fractions in DLD devices by use of a simple model including both advection and diffusion. Our model predicts multidirectional sorting modes that could be experimentally tested in high-throughput DLD devices containing obstacles that are much smaller than the separation between obstacles.
确定性侧向位移(DLD)装置利用障碍物阵列中的层流微流体,根据溶液中微米级颗粒的大小对其进行分离。我们通过使用一个同时包含平流和扩散的简单模型,研究了DLD装置中具有合理行移分数的阵列几何结构。我们的模型预测了多方向分选模式,这些模式可在包含比障碍物间距小得多的障碍物的高通量DLD装置中进行实验测试。