Hyre Amanda D, Krousel-Wood Marie A, Muntner Paul, Kawasaki Lumie, DeSalvo Karen B
School of Public Health and Tropical Medicine, Department of Epidemiology, Tulane University, and Ochsner Clinic Foundation, Center for Health Research, New Orleans, LA 70121, USA.
J Clin Hypertens (Greenwich). 2007 Mar;9(3):179-86. doi: 10.1111/j.1524-6175.2007.06372.x.
Poor medication adherence may contribute to low hypertension control rates. In 2005, 295 hypertensive patients who reported taking antihypertensive medication were administered a telephone questionnaire including an 8-item scale assessing medication adherence. Overall, 35.6%, 36.0%, and 28.4% of patients were determined to have good, medium, and poor medication adherence, respectively. After multivariable adjustment, adults younger than 50 years and 51 to 60 years were 1.39 (95% confidence interval [CI], 0.56-3.42) and 1.53 (95% CI, 0.64-3.66), respectively, times more likely to be less adherent when compared with their counterparts who were older than 60 years. Black adults and men were 4.30 (95% CI, 1.06-17.5) and 2.45 (95% CI, 1.04-5.78) times more likely to be less adherent, respectively. Additionally, caring for dependents, an initial diagnosis of hypertension within 10 years, being uncomfortable about asking the doctor questions, and wanting to spend more time with the doctor if possible were associated with poor medication adherence. The current study identified a set of risk factors for poor antihypertensive medication adherence in the urban setting.
用药依从性差可能导致高血压控制率较低。2005年，对295名报告正在服用抗高血压药物的高血压患者进行了电话问卷调查，其中包括一个评估用药依从性的8项量表。总体而言，分别有35.6%、36.0%和28.4%的患者被确定为用药依从性良好、中等和较差。经过多变量调整后，50岁以下和51至60岁的成年人与60岁以上的成年人相比，用药依从性较差的可能性分别高出1.39倍（95%置信区间[CI]，0.56 - 3.42）和1.53倍（95%CI，0.64 - 3.66）。黑人成年人和男性用药依从性较差的可能性分别高出4.30倍（95%CI，1.06 - 17.5）和2.45倍（95%CI，1.04 - 5.78）。此外，照顾受抚养人、高血压初诊在10年内、对向医生提问感到不舒服以及如果可能想花更多时间与医生在一起，都与用药依从性差有关。当前研究确定了城市环境中抗高血压药物用药依从性差的一系列风险因素。
