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欧洲的恰加斯心脏病:一种新出现的疾病?

Chagas' heart disease in Europe: an emergent disease?

作者信息

Dobarro David, Gomez-Rubin Carmen, Sanchez-Recalde Angel, Olias Fernando, Bret-Zurita Montserrat, Cuesta-Lopez Emilio, Robles-Marhuenda Angel, Fraile-Vicente Jose Maria, Paño-Pardo Jose Ramon, Lopez-Sendon Jose

机构信息

Departments of Cardiology, Spain bRadiology, Spain cInternal Medicine, La Paz University Hospital, Madrid, Spain.

出版信息

J Cardiovasc Med (Hagerstown). 2008 Dec;9(12):1263-7. doi: 10.2459/JCM.0b013e32830eb6fe.

Abstract

Chagas' disease is caused by Trypanosoma Cruzi. It is considered as endemic in central and South America and is transmitted by several species of triatomic bedbug. However, there are other important ways of transmission between humans: vertical transmission and, above all, through blood products and transplants. In Chagas' disease, cardiac disturbances are the most important cause of morbidity, and they usually take place in the chronic stage. The symptoms are the same as in other dilated cardiomyopathies. The management of Chagas' heart disease may be even more difficult than other dilated cardiomyopathies. The increasing number of immigrants from endemic areas of Chagas' disease to developed countries would cause a radical increase in the incidence of this disease over the next years, however European cardiologists are unfamiliar with the disease. In this manuscript, we present our experience in order to stress the necessity of bearing Chagas' disease in mind as a possible cause of dilated cardiomyopathy in patients from endemic areas.

摘要

恰加斯病由克氏锥虫引起。该病在中美洲和南美洲被视为地方病,由多种锥蝽传播。然而,人与人之间还有其他重要的传播途径:垂直传播,尤其是通过血液制品和移植传播。在恰加斯病中,心脏紊乱是发病的最重要原因,且通常发生在慢性阶段。其症状与其他扩张型心肌病相同。恰加斯心脏病的治疗可能比其他扩张型心肌病更困难。从恰加斯病流行地区移民到发达国家的人数不断增加,这将导致未来几年该病发病率急剧上升,然而欧洲心脏病专家对该病并不熟悉。在本手稿中,我们介绍我们的经验,以强调必须将恰加斯病视为来自流行地区患者扩张型心肌病的可能病因。

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