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[查加斯病在欧洲的出现:法国本土拉丁美洲移民中首例病例的描述]

[Emergence of Chagas' disease in Europe: description of the first cases observed in Latin American immigrants in mainland France].

作者信息

Develoux M, Lescure F X, Jaureguiberry S, Jeannel D, Elghouzzi M H, Gay F, Paris L, Le Loup G, Danis M, Pialoux G

机构信息

Service des maladies infectieuses et tropicales, Hôpital Tenon APHP.

出版信息

Med Trop (Mars). 2010 Feb;70(1):38-42.

Abstract

This article describes the first cases of imported Chagas' disease detected in Paris, France. A total of 18 cases were recorded in two teaching hospitals between 2004 and 2007. There were 12 women and six men with a mean age of 38 years. All patients were Latin American immigrants who had recently arrived in France from Bolivia (Cochabamba and Santa-Cruz departments) 17 cases and from Salvador in 1. Eleven patients presented an asymptomatic indeterminate form of the chronic disease. Seven presented chronic Chagas cardiomyopathy including two with severe symptoms requiring placement of a pacemaker. Obtaining serological tests to confirm the diagnosis was difficult. All except one patient who was older than 50 years were treated with benznidazole. Based on these findings, the main priorities for management imported Chagas' disease in France are improvement of serological diagnosis and prevention of vertical transmission.

摘要

本文描述了在法国巴黎首次检测到的输入性恰加斯病病例。2004年至2007年期间,两家教学医院共记录了18例病例。其中12名女性和6名男性,平均年龄38岁。所有患者均为拉丁美洲移民,最近从玻利维亚(科恰班巴和圣克鲁斯省)抵达法国的有17例,从萨尔瓦多抵达的有1例。11名患者表现为无症状的慢性疾病不确定形式。7名患者患有慢性恰加斯心肌病,其中2名症状严重,需要植入起搏器。通过血清学检测来确诊很困难。除了一名年龄超过50岁的患者外,所有患者均接受了苯硝唑治疗。基于这些发现,法国管理输入性恰加斯病的主要优先事项是改善血清学诊断和预防垂直传播。

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