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[荷兰的恰加斯病:患者数量估计]

[Chagas disease in the Netherlands: an estimate of the number of patients].

作者信息

Bart Aldert, Hodiamont Caspar J, Grobusch Martin P, van den Brink Reneé B A, Smout André J P M, van Gool Tom

机构信息

Academisch Medisch Centrum, Amsterdam, the Netherlands.

出版信息

Ned Tijdschr Geneeskd. 2011;155:A3170.

Abstract

A total of 8-10 million persons are infected worldwide with Trypanosoma cruzi, the causative parasite of Chagas disease, most of whom are inhabitants of Latin America. Due to the increased migration of peoples, Chagas disease has been on the uprise outside Latin America, including in Europe. The course of Chagas, also called American trypanosomiasis, runs in 2 phases: an acute phase lasting approximately 2 months, and a chronic phase in which symptoms may appear years after infection. Without treatment, the patient will remain infected for life. The acute phase is usually asymptomatic; in the chronic phase of American trypanosomiasis, severe gastro-intestinal and cardiac abnormalities may develop, finally with fatal course. In the Netherlands, the number of immigrants who would serologically test positive for American trypanosomiasis is estimated to be between 726 and 2929. Healthcare providers in the Netherlands may encounter patients who have Chagas disease more and more frequently. The screening of pregnant women and blood donors at risk for American trypanosomiasis should be considered.

摘要

全球共有800万至1000万人感染了克氏锥虫,这是恰加斯病的致病寄生虫,其中大多数是拉丁美洲居民。由于人口迁移增加,恰加斯病在拉丁美洲以外地区,包括欧洲,呈上升趋势。恰加斯病,也称为美洲锥虫病,病程分为两个阶段:急性期持续约2个月,慢性期症状可能在感染数年之后出现。未经治疗,患者将终身感染。急性期通常无症状;在美洲锥虫病的慢性期,可能会出现严重的胃肠和心脏异常,最终导致致命后果。在荷兰,估计血清学检测呈美洲锥虫病阳性的移民人数在726至2929人之间。荷兰的医疗服务提供者可能会越来越频繁地遇到患有恰加斯病的患者。应考虑对有美洲锥虫病风险的孕妇和献血者进行筛查。

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