Glickstein Mitchell, Doron Karl
Department of Cell and Developmental Biology, University College London, London, UK.
Cerebellum. 2008;7(4):589-94. doi: 10.1007/s12311-008-0074-4. Epub 2008 Nov 11.
In addition to its role in motor control, reflex adaptation, and motor learning, three sorts of evidence have been put forward to support the idea that the cerebellum may also be involved in cognition. Patients with cerebellar lesions are reported to have deficits in performing one or another cognitive task. The cerebellum is often seen to be activated when normal subjects perform such tasks. There are connections to and from areas of the prefrontal cortex that may be involved in cognition. In this paper, we review the anatomical evidence to support the claim. We suggest that there are only minor connections with cognitive areas of the cerebral cortex and that some of the imaging evidence may reflect the cerebellum's role in the control of eye movements rather than cognition.
除了在运动控制、反射适应和运动学习中的作用外,还提出了三类证据来支持小脑可能也参与认知的观点。据报道,患有小脑病变的患者在执行一种或另一种认知任务时存在缺陷。当正常受试者执行此类任务时,经常会看到小脑被激活。与可能参与认知的前额叶皮质区域存在往返连接。在本文中,我们回顾了解剖学证据以支持这一说法。我们认为与大脑皮质认知区域只有少量连接,并且一些成像证据可能反映了小脑在控制眼球运动而非认知方面的作用。