Regulation of keratin and integrin gene expression in cancer and drug resistance.
作者信息
Daly N, Meleady P, Walsh D, Clynes M
机构信息
National Cell and Tissue Culture Centre, BioResearch Ireland, Dublin City University, Glasnevin, Dublin 9, Ireland.,
出版信息
Cytotechnology. 1998 Sep;27(1-3):321-44. doi: 10.1023/A:1008066216490.
Abstract
摘要
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本文引用的文献
1
The relationships among adhesion, stratification and differentiation in keratinocytes.角质形成细胞黏附、分层和分化之间的关系。
Cell Death Differ. 1996 Oct;3(4):357-71.
2
Cytokeratin expression results in a drug-resistant phenotype to six different chemotherapeutic agents.细胞角蛋白的表达导致对六种不同化疗药物产生耐药表型。
Clin Cancer Res. 1996 Jan;2(1):97-105.
3
A regulatory element within a coding exon modulates keratin 18 gene expression in transgenic mice.编码外显子内的一个调控元件调节转基因小鼠中的角蛋白18基因表达。
J Biol Chem. 1997 Oct 31;272(44):27549-57. doi: 10.1074/jbc.272.44.27549.
4
Identification of the human alpha6 integrin gene promoter.人类α6整合素基因启动子的鉴定
DNA Cell Biol. 1997 Aug;16(8):929-37. doi: 10.1089/dna.1997.16.929.
5
The selective engulfment of apoptotic bodies by dendritic cells is mediated by the alpha(v)beta3 integrin and requires intracellular and extracellular calcium.树突状细胞对凋亡小体的选择性吞噬由α(v)β3整合素介导，且需要细胞内和细胞外钙。
Eur J Immunol. 1997 Aug;27(8):1893-900. doi: 10.1002/eji.1830270812.
6
PU.1 negatively regulates the CD11c integrin gene promoter through recognition of the major transcriptional start site.PU.1 通过识别主要转录起始位点对 CD11c 整合素基因启动子进行负调控。
Eur J Immunol. 1997 Aug;27(8):1843-7. doi: 10.1002/eji.1830270804.
7
Human type I cytokeratin genes are a compact cluster.人类I型细胞角蛋白基因是一个紧密的基因簇。
Cytogenet Cell Genet. 1997;77(3-4):169-74. doi: 10.1159/000134566.
8
Co-expression of MDR-associated markers, including P-170, MRP and LRP and cytoskeletal proteins, in three resistant variants of the human ovarian carcinoma cell line, OAW42.多药耐药相关标志物（包括P-170、多药耐药相关蛋白和肺耐药蛋白）与细胞骨架蛋白在人卵巢癌细胞系OAW42的三个耐药变体中的共表达。
Eur J Cancer. 1997 Apr;33(4):652-60. doi: 10.1016/s0959-8049(96)00501-1.
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Methylation of an ETS site in the intron enhancer of the keratin 18 gene participates in tissue-specific repression.角蛋白18基因内含子增强子中ETS位点的甲基化参与组织特异性抑制。
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Loss of matrix adhesion triggers rapid transformation-selective apoptosis in fibroblasts.基质黏附丧失引发成纤维细胞中快速的转化选择性凋亡。
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