Rodrigo Guillermo, Carrera Javier, Jaramillo Alfonso
IBMCP, CSIC-UPV, Camino de Vera s/n, 46022, Valencia, Spain.
Syst Synth Biol. 2007 Dec;1(4):167-70. doi: 10.1007/s11693-008-9013-4. Epub 2008 Mar 26.
We propose a new computational tool to produce models of biological systems by assembling models from biological parts. Our software not only takes advantage of modularity, but it also enforces standardisation in part characterisation by considering a model of each part. We have used model parts in SBML to design transcriptional networks. Our software is open source, it works in linux and windows platforms, and it could be used to automatically produce models in a server. Our tool not only facilitates model design, but it will also help to promote the establishment of a registry of model parts.
我们提出了一种新的计算工具，通过组装生物部件的模型来生成生物系统模型。我们的软件不仅利用了模块化，还通过考虑每个部件的模型来强化部件表征的标准化。我们已使用SBML中的模型部件来设计转录网络。我们的软件是开源的，可在Linux和Windows平台上运行，还可用于在服务器上自动生成模型。我们的工具不仅便于模型设计，还将有助于推动建立一个模型部件注册库。
