Eschner Andrew K
Merial Limited, 4 Pepper Place, Gansevoort, NY 12381, USA.
Vet Ther. 2008 Fall;9(3):184-91.
The event that 8 of 12 pups born to a Lyme borreliosis-positive dam tested positive on a commonly used in-hospital Lyme borreliosis test kit at 1 week of age prompted breeder concern about the possibility and implications of transplacental Lyme borreliosis infection. Almost 2 weeks after the initial serologic test results were obtained, blood was collected from the puppies for comprehensive testing. Assessment of the findings indicate the possibility that passive transfer of maternally derived antibody to the in vivo expressed C6 peptide of Borrelia burgdorferi can temporarily render pups serologically positive for antibodies on the in-hospital C6 Lyme borreliosis antibody test kit when the test is run on very young animals.
一只莱姆病伯氏疏螺旋体呈阳性的母犬所生的12只幼犬中有8只在1周龄时使用常用的医院内莱姆病伯氏疏螺旋体检测试剂盒检测呈阳性，这一事件引发了饲养者对经胎盘感染莱姆病伯氏疏螺旋体的可能性及影响的担忧。在获得初始血清学检测结果近2周后，从幼犬身上采集血液进行全面检测。对检测结果的评估表明，母源抗体向体内表达的伯氏疏螺旋体C6肽的被动转移可能会使幼犬在使用医院内C6莱姆病伯氏疏螺旋体抗体检测试剂盒对非常年幼的动物进行检测时暂时在血清学上呈抗体阳性。
