Bloomer Richard J
Department of Health and Sport Sciences, The University of Memphis, Memphis, Tennessee 38152, USA.
Adv Clin Chem. 2008;46:1-50. doi: 10.1016/s0065-2423(08)00401-0.
Acute bouts of aerobic and anaerobic exercise can induce a state of oxidative stress, as indicated by an increase in oxidized molecules in a variety of tissues and body fluids. The extent of oxidation is dependent on the exercise mode, intensity, and duration, and is specifically related to the degree of oxidant production. Findings of increased oxidative stress have been reported for both healthy and diseased subjects following single bouts of exercise. While acute exercise has the ability to induce an oxidative stress, this same exercise stimulus appears necessary to allow for an upregulation in endogenous antioxidant defenses. This chapter presents a summary of exercise-induced oxidative stress.
如各种组织和体液中氧化分子增加所示,有氧和无氧运动的急性发作可诱发氧化应激状态。氧化程度取决于运动模式、强度和持续时间,尤其与氧化剂产生的程度有关。单次运动后,健康和患病受试者均有氧化应激增加的报道。虽然急性运动有诱发氧化应激的能力,但同样的运动刺激似乎也是上调内源性抗氧化防御所必需的。本章概述了运动诱导的氧化应激。