波兰首次分离出艰难梭菌PCR核糖体分型027/毒素分型III。
First isolation of Clostridium difficile PCR-ribotype 027/toxinotype III in Poland.
作者信息
Pituch Hanna, Bakker Dennis, Kuijper Ed, Obuch-Woszczatyński Piotr, Wultańska Dorota, Nurzyńska Grazyna, Bielec Anna, Bar-Andziak Ewa, Łuczak Mirosław
机构信息
Chair and Department of Medical Microbiology, The Medical University of Warsaw, Warsaw, Poland.
出版信息
Pol J Microbiol. 2008;57(3):267-8.
Of 175 Clostridium difficile strains isolated from patient hospitalized in one academic hospital in Warsaw between 2005-2006, one isolate belonged to PCR-ribotype 027/toxinotype III. This isolate had tcdA, tcdB, binary toxin genes (cdtA and cdtB), a 18-bp deletion and a 1 bp deletion at 117 position in the tcdC gene. Antimicrobial susceptibility tests revealed high level resistance to erythromycin, moxifloxacin and gatifloxacin. This is a first report of the 027 strain of C. difficile in Poland.
在2005年至2006年间从华沙一家学术医院住院患者中分离出的175株艰难梭菌菌株中，有一株属于PCR核糖体分型027/毒素型III。该分离株具有tcdA、tcdB、二元毒素基因（cdtA和cdtB），tcdC基因在117位有一个18 bp的缺失和一个1 bp的缺失。药敏试验显示对红霉素、莫西沙星和加替沙星高度耐药。这是波兰艰难梭菌027菌株的首次报告。
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