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艰难梭菌核糖体分型176的抗生素敏感性分析——一种相对于艰难梭菌核糖体分型027的多重耐药菌

Antibiotic profiling of Clostridium difficile ribotype 176--A multidrug resistant relative to C. difficile ribotype 027.

作者信息

Krutova Marcela, Matejkova Jana, Tkadlec Jan, Nyc Otakar

机构信息

Department of Medical Microbiology, 2nd Faculty of Medicine, Charles University in Prague and University Hospital in Motol, Czech Republic; DNA laboratory, Department of Paediatric Neurology, 2nd Faculty of Medicine, Charles University in Prague and University Hospital in Motol, Czech Republic.

Department of Medical Microbiology, 2nd Faculty of Medicine, Charles University in Prague and University Hospital in Motol, Czech Republic.

出版信息

Anaerobe. 2015 Dec;36:88-90. doi: 10.1016/j.anaerobe.2015.07.009. Epub 2015 Aug 6.

DOI:10.1016/j.anaerobe.2015.07.009
PMID:26256807
Abstract

Antibiotic profiling of twenty Czech Clostridium difficile PCR-ribotype 176 isolates revealed a high level of resistance to erythromycin, ciprofloxacin and moxifloxacin (n = 20) and to rifampicin (n = 13). Accumulation of resistance mechanisms to multiple antibiotics highlight that PCR-ribotype 176 belong to problematic epidemic strains.

摘要

对20株捷克艰难梭菌PCR核糖体分型176菌株进行的抗生素敏感性分析显示，这些菌株对红霉素、环丙沙星和莫西沙星（n = 20）以及利福平（n = 13）具有高度耐药性。对多种抗生素耐药机制的积累表明，PCR核糖体分型176属于有问题的流行菌株。

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