咪喹莫特治疗外阴佩吉特病：一例报告
Imiquimod in vulvar Paget's disease: a case report.
作者信息
Geisler John P, Manahan Kelly J
机构信息
Indiana Women's Oncology, Division of Gynecologic Oncology, St. Vincent Hospitals, Indianapolis, IN 46260, USA.
出版信息
J Reprod Med. 2008 Oct;53(10):811-2.
BACKGROUND
Vulvar Paget's disease is a relatively rare gynecologic neoplasm that is problematic because of its propensity to recur.
CASE
An 80-year-old woman was found to have recurrent Paget's disease of the vulva. She was initially diagnosed 12 years previously and had had multiple resections for the disease. She was found to have histologically proven Paget's disease and underwent a course of topical immune modulator therapy with imiquimod. Biopsy proved histologic regression of the disease progress. The patient remained without recurrence 12 months after therapy.
CONCLUSION
In select patients imiquimod may be used to treat or facilitate treatment of vulvar Paget's disease.
背景
外阴佩吉特病是一种相对罕见的妇科肿瘤，因其易于复发而成为难题。
病例
一名80岁女性被发现患有复发性外阴佩吉特病。她最初于12年前被诊断出该病，并且已经针对该疾病进行了多次切除手术。她经组织学证实患有佩吉特病，并接受了咪喹莫特局部免疫调节剂治疗疗程。活检证明疾病进展出现组织学消退。治疗12个月后，患者未再复发。
结论
在特定患者中，咪喹莫特可用于治疗或辅助治疗外阴佩吉特病。
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