Farsang C, Naditch-Brule L, Perlini S, Zidek W, Kjeldsen S E
The Cardiometabolic Centre, St Imre Hospital, Budapest, Hungary.
J Hum Hypertens. 2009 May;23(5):316-24. doi: 10.1038/jhh.2008.136. Epub 2008 Nov 13.
The GOOD survey investigated the global cardiometabolic risk profile in adult patients with hypertension across 289 sites in four European regions (Northwest, Mediterranean, Atlantic European Mainland and Central Europe). Demographic, lifestyle, clinical and laboratory data were collected from eligible patients (n=3370) during a single clinic visit. In Central Europe, represented by Hungary, 44% of the participants had type II diabetes compared with 33% in the Atlantic European Mainland, and 26% in the Northwest and the Mediterranean regions. The prevalence of metabolic syndrome was also significantly higher in Central Europe (68%) and the Atlantic European Mainland (60%) than in the Northwest and the Mediterranean regions (50 and 52%, respectively). Fasting blood glucose, total cholesterol and triglyceride levels were all highest in Central Europe compared with the other three regions (P<0.001). In the Atlantic European Mainland, more patients had uncontrolled blood pressure (80%) compared with the other three regions (70-71%). Declared alcohol consumption was highest in the Atlantic European Mainland and exercise lowest in Central Europe. The prevalence of congestive heart failure, left ventricular hypertrophy, coronary artery disease and stable/unstable angina was higher in Central Europe compared with the other regions, whereas a family history of premature stroke or myocardial infarction, stroke, coronary revascularization and transient ischaemic attacks was all highest in the Atlantic European Mainland. These data indicate that many hypertensive patients across Europe have multiple cardiometabolic risk factors with the prevalence higher in Central Europe and the Atlantic European Mainland compared with Northwest and Mediterranean regions.
“良好”（GOOD）调查研究了欧洲四个地区（西北、地中海、大西洋欧洲大陆和中欧）289个地点的成年高血压患者的全球心血管代谢风险状况。在一次门诊就诊期间，从符合条件的患者（n = 3370）中收集了人口统计学、生活方式、临床和实验室数据。以匈牙利为代表的中欧地区，44%的参与者患有II型糖尿病，而在大西洋欧洲大陆这一比例为33%，在西北和地中海地区则为26%。中欧（68%）和大西洋欧洲大陆（60%）的代谢综合征患病率也显著高于西北和地中海地区（分别为50%和52%）。与其他三个地区相比，中欧的空腹血糖、总胆固醇和甘油三酯水平均最高（P<0.001）。在大西洋欧洲大陆，与其他三个地区（70 - 71%）相比，有更多患者血压控制不佳（80%）。宣称的酒精消费量在大西洋欧洲大陆最高，而锻炼量在中欧最低。与其他地区相比，中欧充血性心力衰竭、左心室肥厚、冠状动脉疾病和稳定/不稳定型心绞痛的患病率更高，而早发性中风或心肌梗死的家族史、中风、冠状动脉血运重建和短暂性脑缺血发作在大西洋欧洲大陆的患病率均最高。这些数据表明，欧洲许多高血压患者存在多种心血管代谢危险因素，中欧和大西洋欧洲大陆的患病率高于西北和地中海地区。
