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转移性乳腺癌女性患者的抑郁症:文献综述

Depression in women with metastatic breast cancer: a review of the literature.

作者信息

Caplette-Gingras Aude, Savard Josée

机构信息

School of Psychology, Université Laval, Québec, Québec, Canada.

出版信息

Palliat Support Care. 2008 Dec;6(4):377-87. doi: 10.1017/S1478951508000606.

DOI:10.1017/S1478951508000606
PMID:19006593
Abstract

OBJECTIVE

The aim of this article is to review the available literature on depression in women with metastatic breast cancer in terms of prevalence, potential risk factors, and consequences, as well as pharmacological and psychological interventions.

METHOD

An extensive review of the literature was conducted.

RESULTS

The prevalence of depression appears to be especially elevated in patients with advanced cancer. Many demographic, medical, and psychosocial factors may increase the risk that women will develop depressive symptoms during the course of their illness. Despite the fact that depression appears to be associated with numerous negative consequences, this disorder remains underdiagnosed and undertreated. Both pharmacotherapy and psychotherapy have been found to treat effectively depressive symptoms in this population, but cognitive-behavioral therapy appears to be the most cost-effective approach.

SIGNIFICANCE OF RESULTS

Areas for future research are suggested.

摘要

目的

本文旨在综述转移性乳腺癌女性患者抑郁症的现有文献,内容涉及患病率、潜在风险因素、后果以及药物和心理干预措施。

方法

对文献进行了广泛综述。

结果

晚期癌症患者中抑郁症的患病率似乎尤其高。许多人口统计学、医学和社会心理因素可能会增加女性在患病过程中出现抑郁症状的风险。尽管抑郁症似乎与众多负面后果相关,但这种疾病仍未得到充分诊断和治疗。药物治疗和心理治疗均已被证实能有效治疗该人群的抑郁症状,但认知行为疗法似乎是最具成本效益的方法。

结果的意义

提出了未来研究的方向。

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