Park Byong-Gon, Kwon Seong-Chun, Park Gab-Man, Ham Jungyeob, Shin Woon-Seob, Lee Seokjoon
Department of Physiology, Kwandong University College of Medicine, Gangneung 210-701, Republic of Korea.
Bioorg Med Chem Lett. 2008 Dec 15;18(24):6324-6. doi: 10.1016/j.bmcl.2008.10.103. Epub 2008 Oct 26.
Two farnesylacetones, 311 and 312, major active constituents of Sargassum siliquastrum collected from the coast of the East Sea in Korea, showed a moderate vasodilatation effect on the basilar arteries of rabbits. Therefore, treatment with farnesylacetones 311 and 312 may selectively accelerate cerebral blood flow through dilatation of the basilar artery.
从韩国东海沿岸采集的羊栖菜的两种主要活性成分法呢基丙酮311和312，对兔基底动脉显示出适度的血管舒张作用。因此，用311和312法呢基丙酮治疗可能通过基底动脉扩张选择性地加速脑血流。
