He Wen, Jiang Xiao-qian, Wang Shuo, Zhang Mao-zhi, Zhao Ji-zong, Liu Hui-zhao, Ma Jun, Xiang Dong-ying, Wang Li-shu
Department of Ultrasound, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.
Clin Imaging. 2008 Nov-Dec;32(6):419-24. doi: 10.1016/j.clinimag.2008.05.006.
The purpose of this study was to investigate the feasibility and value of the intraoperative contrast-enhanced ultrasound (CEUS) in resection for brain tumors.
Intraoperative CEUS was performed in 29 patients with brain tumors pre-resection, in whom 9 (of 29) patients underwent second intraoperative CEUS for assessing remained tumor tissue after initial resection. Gray-scale and color-flow images of the brain tumors on both conventional and CEUS were analyzed and compared with the results of surgical pathology.
The border of the tumor and remained tumor tissue was more distinguishable from healthy brain on CEUS than that on conventional ultrasound during the operation. Improving definition of the tumor tissue from normal brain with CEUS was demonstrated in all cases.
Intraoperative CEUS has the potential to be a very useful imaging technique not only in defining the border between the tumor and healthy brain pre resection but also in detecting remained tumor tissues after the initial resection.
本研究旨在探讨术中超声造影（CEUS）在脑肿瘤切除术中的可行性及价值。
对29例脑肿瘤患者在切除术前进行术中CEUS检查，其中9例（共29例）患者在初次切除术后进行二次术中CEUS检查以评估残留肿瘤组织。分析并比较常规超声和CEUS检查下脑肿瘤的灰阶和彩色血流图像，并与手术病理结果进行对比。
术中CEUS检查显示肿瘤边界及残留肿瘤组织与正常脑组织的区分度比常规超声更好。所有病例均显示CEUS检查能提高肿瘤组织与正常脑组织的分辨度。
术中CEUS不仅在术前界定肿瘤与正常脑组织边界方面，而且在初次切除术后检测残留肿瘤组织方面都有可能成为一种非常有用的成像技术。
