Golombek Sergio G
The Regional Neonatal Center-Maria Fareri Children's Hospital at Westchester Medical Center/New York Medical College, Valhalla, New York 10595, USA.
Semin Perinatol. 2008 Dec;32(6):413-8. doi: 10.1053/j.semperi.2008.09.010.
This article reviews the pathophysiology of non-thyroidal illness syndrome (NTIS) and euthyroid sick syndrome (ESS), a multifactorial phenomenon characterized by suppression of thyroid hormone levels that has been described in several disease states, probably due to different causes in different patients. It also describes the laboratory values of thyroid function tests (TFTs), relevant animal studies, the association of NTIS and ESS with cardiovascular problems and sepsis, and the rationale for treatment.
本文综述了非甲状腺疾病综合征（NTIS）和正常甲状腺病态综合征（ESS）的病理生理学，这是一种多因素现象，其特征为甲状腺激素水平受到抑制，在多种疾病状态中均有描述，不同患者的病因可能不同。文章还介绍了甲状腺功能检查（TFTs）的实验室值、相关动物研究、NTIS和ESS与心血管问题及脓毒症的关联，以及治疗的理论依据。
