原发性颈段脊髓生殖细胞瘤的同步放化疗

Concurrent chemoradiotherapy for primary cervical spinal cord germinoma.

作者信息

Yang Ka-Yen, Li Shau-Hsuan, Lin Jui-Wei, Su Thung-Ming, Ho Jih-Tsun, Chen Wu-Fu

机构信息

Department of Neurosurgery, Chang Gung Memorial Hospital - Kaohsiung Medical Center, Chang Gung University College of Medicine, 123 Ta-Pei Road, Niao-Sung Hsiang, Kaohsiung 833, Taiwan.

出版信息

J Clin Neurosci. 2009 Jan;16(1):115-8. doi: 10.1016/j.jocn.2007.11.019. Epub 2008 Nov 12.

DOI:10.1016/j.jocn.2007.11.019

PMID:19008102

Abstract

We report a rare case of primary intramedullary germinoma in the cervical spine of a 39-year-old woman without evidence of intracranial or disseminated disease. The germinoma was treated by a biopsy and follow-up concurrent chemoradiotherapy. This is the only reported case of primary spinal cord germinoma for which concurrent chemoradiotherapy was given. Furthermore, this is only the second reported case of histologically documented primary intramedullary cervical spinal cord germinoma. The patient was disease-free and there was near-complete resolution of the pre-operative neurological deficits at the 20-month follow-up examination.

摘要

我们报告了一例罕见的原发性脊髓生殖细胞瘤病例，患者为一名39岁女性，颈椎发病，无脑内或播散性疾病证据。该生殖细胞瘤通过活检及后续同步放化疗进行治疗。这是唯一一例报道的接受同步放化疗的原发性脊髓生殖细胞瘤病例。此外，这也是第二例经组织学证实的原发性颈段脊髓髓内生殖细胞瘤病例。在20个月的随访检查中，患者无疾病复发，术前神经功能缺损几乎完全恢复。