Franco Eugênio Santana, Hyppólito Silvia Bomfim, Franco Rosana Gomes de Freitas Menezes, Oriá Mônica Oliveira Batista, Almeida Paulo César de, Pagliuca Lorita Marlena Freitag, Rocha Nelson Fernando Pacheco da
Escola Superior de Saúde, Universidade de Aveiro, Aveiro, Portugal.
Cad Saude Publica. 2008 Nov;24(11):2653-60. doi: 10.1590/s0102-311x2008001100020.
This study aimed to validate the scoring criteria for digital cervicography. The study enrolled 300 women submitted to a clinical protocol using cytological examination alone, digital cervicography without image magnification (Evaluation 1), and digital cervicography plus additional image magnification and considering the positive criteria (Evaluation 2). Women's mean age was 27.6 years. Positive criteria for digital cervicography were identified in 111 positive cases with pre-cancerous cervical lesions (100%) and in 8 cases classified as false positives (2.6%). Evaluations 1 and 2 classified the tests as positive (163; 54.3%) and suspected (146; 48.6%), respectively. According to the findings, digital cervicography was more sensitive (99.1%) and cytology more specific (100%). Digital cervicography sensitivity increased by 4.5 times when the positive criteria were applied as compared to cytology alone, besides involving low cost, thus suggesting that it is a viable technique.
本研究旨在验证数字宫颈造影的评分标准。该研究纳入了300名女性，她们接受了单独使用细胞学检查、无图像放大的数字宫颈造影（评估1）以及数字宫颈造影加额外图像放大并考虑阳性标准（评估2）的临床方案。女性的平均年龄为27.6岁。在111例宫颈癌前病变阳性病例（100%）和8例被分类为假阳性的病例（2.6%）中确定了数字宫颈造影的阳性标准。评估1和评估2分别将检测结果分类为阳性（163例；54.3%）和疑似阳性（146例；48.6%）。根据研究结果，数字宫颈造影更敏感（99.1%），而细胞学更具特异性（100%）。与单独使用细胞学检查相比，应用阳性标准时数字宫颈造影的敏感性提高了4.5倍，而且成本较低，因此表明它是一种可行的技术。
