Bateman Allen C, Parham Groesbeck P, Sahasrabuddhe Vikrant V, Mwanahamuntu Mulindi H, Kapambwe Sharon, Katundu Katundu, Nkole Theresa, Mulundika Jacqueline, Pfaendler Krista S, Hicks Michael L, Shibemba Aaron, Vermund Sten H, Stringer Jeffrey S A, Chibwesha Carla J
*Centre for Infectious Disease Research in Zambia, Lusaka, Zambia; †University of North Carolina at Chapel Hill, Chapel Hill, NC; ‡University Teaching Hospital, Lusaka, Zambia; §Vanderbilt University, Nashville, TN; ‖University of Cincinnati, Cincinnati, OH; and ¶Michigan Cancer Institute, Pontiac, MI.
J Acquir Immune Defic Syndr. 2014 Oct 1;67(2):212-5. doi: 10.1097/QAI.0000000000000270.
Although there is a growing literature on the clinical performance of visual inspection with acetic acid in HIV-infected women, to the best of our knowledge, none have studied visual inspection with acetic acid enhanced by digital cervicography. We estimated clinical performance of cervicography and cytology to detect cervical intraepithelial neoplasia grade 2 or worse. Sensitivity and specificity of cervicography were 84% [95% confidence interval (CI): 72 to 91) and 58% (95% CI: 52 to 64). At the high-grade squamous intraepithelial lesion or worse cutoff for cytology, sensitivity and specificity were 61% (95% CI: 48 to 72) and 58% (95% CI: 52 to 64). In our study, cervicography seems to be as good as cytology in HIV-infected women.
虽然关于醋酸目视检查在感染HIV女性中的临床应用的文献越来越多，但据我们所知，尚无研究探讨数字宫颈造影增强的醋酸目视检查。我们评估了宫颈造影和细胞学检查检测宫颈上皮内瘤变2级或更严重病变的临床效能。宫颈造影的灵敏度和特异度分别为84%[95%置信区间（CI）：72至91]和58%（95%CI：52至64）。在细胞学检查的高级别鳞状上皮内病变或更严重病变的临界值时，灵敏度和特异度分别为61%（95%CI：48至72）和58%（95%CI：52至64）。在我们的研究中，宫颈造影在感染HIV的女性中似乎与细胞学检查效果相当。
